Grand Theft Auto V : Bus Assassination Walkthrough
Bus Assassination is one of the Grand Theft Auto 5 Missions. In this mission you need to steal a City bus (from the lot Lester sends you to).
Continue to drive the city busy route, picking up passagers and drive normal until you see the target.
The target (who is not polite) will make a run for a bike when he notice you are after him. Use the bus to run him over.